Everything about Isosthenuria totally explained
Isosthenuria refers to the excretion of urine, the
specific gravity (concentration) of which is neither greater (more concentrated) nor less (more dilute) than that of protein-free
plasma. This is the hallmark of such disease states as chronic and acute
renal failure in which the
kidneys lack the ability to concentrate or dilute the
urine and so the initial filtrate of the blood remains unchanged despite the need to conserve or excrete water based on the body's hydration status.
Sickle Cell trait, the heterozygous form of
Sickle Cell disease, presents with a normal hematological picture but is associated with isosthenuria and increased frequency of urinary tract infections.
See also
hyposthenuria and
hypersthenuria.
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